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QUALITY ASSESSMENT OF SILYBUM MARIANUM FRUITS GROWN IN THE REPUBLIC OF BURYATIA

DOI: https://doi.org/10.29296/25877313-2024-03-05
Issue: 
3
Year: 
2024

O.L. Saybel
Dr.Sc. (Pharm.), Head of the Center of Chemistry and Pharmaceutical Technology,
All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow, Russia)
E-mail: saybel@vilarnii.ru
E.A. Konyaeva
Senior Research Scientist, Department of Chemistry of Natural,
All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow, Russia)
E-mail: lencon64@mail.ru
O.Y. Kulyak
Ph.D. (Pharm.), Head of Testing Center,
All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow, Russia)
E-mail: kulyak-olesya@mail.ru
V.N. Dul
Ph.D. (Pharm.), Leading Research Scientist, Department of Chemistry of Natural Compounds,
All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (Moscow, Russia)
E-mail: dvnslava@yandex.ru
O.M. Tsybikova
Ph.D. (Agricul.), Associate Professor, Department of Plant, Meadow and Horticulture,
Buryat State Agricultural Academy named after V.R. Filippov (Ulan-Ude, Republic of Buryatia, Russia)
E-mail: oyuna_sodnom@rambler.ru
B.D. Tsydypov
Senior Lecturer, Department of Plant, Meadow and Horticulture,
Buryat State Agricultural Academy named after V.R. Filippov (Ulan-Ude, Republic of Buryatia, Russia)

Introduction. Medicines of plant origin are widely used in the complex therapy of various diseases. Among the medicines of plant origin used for the treatment of chronic liver diseases, the most popular are preparations based on Silybum marianum (L.) Gaertn.). The aim of this work was to Silybum marianum fruits to evaluate the possibility of obtaining raw materials of pharmacopoeial quality in the dry-steppe zone of the Republic of Buryatia. Material and methods. The object of the study was Silybum marianum fruits of the varieties Debut and Start, obtained from experimental fields in Ivolginsky district of the Republic of Buryatia, as well as samples of Silybum marianum fruits received for analysis at the Testing Center of FGBNU VILAR from different regions of the Russian Federation. Results. As a result of the research it was found that climatic and geographical conditions of the dry-steppe zone of the Republic of Buryatia allow successful cultivation of Silybum marianum and obtaining raw materials (fruits) of pharmacopoeial quality. Conclusion. Silybum marianum fruits obtained from plants of the Start variety are not inferior to similar raw materials harvested in other regions of the Russian Federation in the content of the sum of flavolignans.
Keywords: 
Silybum marianum
Silybum marianum fruits
flavolignans.
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